💊5-Amino-1MQ | 50mg X 25

5-Amino-1MQ is a small molecule derivative of methylquinolinium that acts as an NNMT (Nicotinamide N-Methyltransferase) inhibitor, targeting cellular metabolism and energy homeostasis. NNMT plays a crucial role in regulating nicotinamide and S-adenosylmethionine metabolism, influencing cellular NAD+ levels and impacting metabolic processes such as oxidative phosphorylation and mitochondrial function. By inhibiting NNMT, 5-Amino-1MQ enhances intracellular NAD+ availability, promoting SIRT1 activation, which in turn facilitates mitochondrial biogenesis, fatty acid oxidation, and metabolic efficiency. This leads to increased energy expenditure, reduced adipogenesis, and improved metabolic homeostasis, making it of interest in obesity, metabolic syndrome, and age-related metabolic decline.

Additionally, its role in modulating methylation pathways affects cellular repair mechanisms and overall metabolic flexibility, positioning it as a promising therapeutic candidate for enhancing metabolic efficiency and longevity.